Therapeutic Solutions International Announces Exclusive Patent License Agreement with Subsidiary Emvolio, Inc.

OCEANSIDE, CA–(Marketwired – June 01, 2017) – Therapeutic Solutions International, Inc., (OTC PINK: TSOI) announced today an exclusive licensing agreement with its subsidiary Emvolio, Inc.

The overarching concept is that various concentrations of mifepristone are useful alone, or in combination with other immune stimulants, for upregulation of various components of the immune response.

In particular, the invention teaches that cancer associated molecules, including production of glucocorticoids and HPA activation, have a general suppressive activity on the immune response which blocks ability to elicit effective anticancer immunity. We have developed methods of utilizing mifepristone or its derivatives as monotherapies or combination therapies to facility effective immune response induction.

“Developing the novel immunological use of mifepristone in the area of oncology adds another weapon in the fight against cancer using the patient’s own immune system,” said Timothy Dixon, President and CEO of Therapeutic Solutions International. “Given the established safety profile and known pharmacokinetics of mifepristone, we anticipate significantly reduced risk in its clinical development as compared to novel compositions of matter.”

“Natural killer cells are a unique arm of the immune system that is capable of killing cancer cells without prior sensitization. The findings that mifepristone is capable of reducing cancer associated suppression of the natural killer cell compartment, we believe, positions mifepristone as a potentially valuable therapeutic in utilization of the immune system to kill tumors, ” said Dr. Thomas Ichim, Director of Therapeutic Solutions International and Chief Executive Officer of Emvolio.

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Therapeutic Solutions International, Inc.